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Alzheimer's Disease and beta-amyloid (Abeta)

Edited by: Joe Hing kwok Chu


Inhaled anesthesia can enhance Abeta - oligomerization and cytotoxicity [1]

Light to moderate alcohol consumption is associated withS100beta  and amyloid beta level in healthy older adults. [2]

Using a steroid type of chemical to activates pregnane X receptor (PXR), the amount of beta-amyloid protein in the brain is reduced in the genetically modified mice expressing with human abeta. The activation of the PXR was found to increase the expression of a blood-brain barrier protein known as P-glycoprotein. This protein transports beta-amyloid out of the brain. [3]

Elevated S100beta levels may indicate the presence of radiologically detectable blood brain barrier leakage.[4]

Using benzodiazepine drug may increase the chance of getting Alzheimer's disease. [5]


Back to Alzheimer's D page.

See: beng da wan (Centella Asiatica)






[5] BMJ. 2014; 349: g5205.


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