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Anti HBV Herbs   (in English and Chinese 中英文)

抗乙型肝 炎 病毒之中藥    Click here for mobile users.

by: Joe Hing Kwok Chu  興 國編譯  

Anti HBV Herbs:[2]

抗乙型肝 炎病毒之中藥:[2]

bai hua she she cao

花 蛇舌草

bai shao

白芍

cang zhu

蒼朮

da huang

大黃

dan shen

丹參

dong chong xia cao

冬蟲夏草

feng huang jiang

蜂皇漿

guan ye lian qiao (St, John's wort)

貫葉連

huang qi

黃芪

kong xin lian

空心蓮

ku shen

苦參

li zhi he

荔枝核

ling zhi

靈芝

mu li

牡蠣

popolis

峰膠

royal jerry

蜂皇漿

shu gu jiang huang

束骨薑黃

su xin hua

素磬花, 大茉莉花

xiang fu zi

香附子 [4]

xiao long ji

肖籠雞

yan huang lian

岩黃連

ye xia zhu

下 珠

yun zhi

雲芝

ze xie

澤瀉

 

Table 1.  The top 10 TIs in HBV DNA, HBeAg or HBsAg release displayed by individual TCHM compounds and extracts in HepG2.2.15 cells [1]

No.

HBV DNA

HBeAg

HBsAg

Compounds/Extracts ( Herb names)

TI*

Compounds/Extracts ( Herb names)

TI*

Compounds/Extracts ( Herb names)

TI*

1

Chrysophanol 8-O-beta-D-glucoside (Rheum palmatum, L) 葉 大黃

270.42

Ellagic acid (Phyllanthus urinaria) 下 珠

13371.43

Liposome-encapsulated matrine ( Sophora flavescens. Ait. 苦參)

93.46

2

Artesunate ( Artemisia annua ) 黃花蒿(青蒿)根

40

Water extract ( Hypericum perforatum) 貫葉連

96.34

Water extract ( Cynanchum paniculatum) 徐長卿

80.32

3

Protocatechuic aldehyde ( Salvia multiorrhiza  Bge.) 丹參

17.27

Chrysophanol 8-O-beta-D-glucoside (Rheum palmatum,)錦文大黃

54.52

Nirtetralin B ( Phyllanthus niruri Linn 珠子草)

69.63

4

Ethanol extract ( Polygonum cuspidatum, S. et. Z.) 虎杖

8.53

Wogonin  (  Scutellaria baicalensis  Georg.) 黃芩

50

Water extract (Helicteres angustifolia) 山芝麻

66

5

Ethanol extract (Rheum palmatum, L.) 葉 大黃

7.67

Water extract ( Mallotus apelta) 白背葉

43.08

Baicalin ( Scutellaria baicalensis  Georg). 黃芩

65.22

6

Astragaloside IV ( Astragalus)黃 耆

7.4

Water extract ( Mesona procumbens) 仙草

34.67

Aloe emodin ( Rheum tanguticum) 唐古特大黃

56.74

7

Matrine ( Sophora flavescens. Ait.)

苦參

6.39

Water extract ( Helicteres angustifolia) 山芝麻

33

Wogonin ( Scutellaria baicalensis  Georg.)  黃 芩

50

8

Water extract ( Polygonum cuspidatum, S. et. Z.) 虎 杖

4.76

Ethanol extract ( Hypericum perforatum 貫葉連翹)

31.39

Chrysophanol 8-O-beta-D-glucoside ( Rheum palmatum, L) 葉 大黃

42.12

9

Wogonin ( Scutellaria baicalensis  Georg.)  黃 芩

4.00

Protocatechuic aldehyde ( Salvia multiorrhiza  Bge.丹 參)

29.27

Water extract (  Hypericum perforatum 貫葉連翹)

38.45

10

Saikosaponin c ( Bupleurum species) 柴胡

2.98

Alisol F 24-acetate ( Alisma orientale (Sam.)Juzep.澤 瀉)

28

Terpenoids  ( Strobilanthes affinis 肖籠雞 )

36.99

Lamivudine

30061

Lamivudine

1.16

Lamivudine

2.53

 The inhibitory effect on plasma DHBV DNA by 7 Chinese herbs showing high TIs in HBV DNA, HBeAg or HBsAg release in HepG2.2.15 cells [1]

Herb name

Treatment

No. of ducks

Dosage (mg/kg/day)

Duration (days)

Inhibition rate (%)*

P3 (%)

References

Phyllanthus urinaria  Guangxiensis 葉下珠

Extract

12

5000

30

87.50

53.65

[19]

Phyllanthus urinaria Yunnanensis

Water extract

10

10000

30

77.69

NI

[20]

Phyllanthus urinaria Guangxiensis

Water extract

10

10000

30

60.00

58.73

[20]

Sophora flavescens 苦參

Liposome-encapsulated matrine

6

20

20

76.84

77.53

[12]

Matrine

6

20

20

42.11

33.71

[12]

Rheum palmatum  大黃

Ethanol extract

8

10000

10

64.37

74.17

[14]

Helicteres angustifolia  山芝麻

Water extract

10

10000

14

61.95

51.00

[21]

Water extract

10

10000

14

33.35

25.82

[22]

Scutellaria baicalensis 黃芩

Wogonin

20

10

>50.00

>50.00

[9]

Salvia miltiorrhiza 丹參

Protocatechuic aldehyde

6

100

10

48.40

35.90

[23]

Artemisia annua 青蒿 (黃花蒿)

Artesunate

8

30

28

17.51

NI

[24]

, not reported; NI, no inhibition.
*Highest inhibition in plasma DHBV DNA during the treatment.
Inhibition in plasma DHBV DNA at least 3 days post-treatment withdrawal.

 

TI: the ratio between CC 50 and IC 50.
*CC 50, IC 50 and references are shown in supplementary materials.

Cytotoxicity is the quality of being toxic to cells. The 50% cytotoxic concentration (CC50)

was defined as the concentration required to reduce the cell number by 50% compared to

that for the untreated controls.

The half maximal inhibitory concentration (IC50) is a measure of the effectiveness of a

substance in inhibiting a specific biological or biochemical function.

 

Anti carcinoma formula:

Administration of shi quan da bu tang (pronounced as Juzen-taiho-to in Japanese) prevent

hepatocellular carcinoma development.[3]

 

 

Anti cirrhosis herb:

bie jia

tao ren

xiao hui xiang

dan shen

xu chang qing ( Cynanchum paniculatum (Bge.) Kitag.)

 

肝硬化之中藥:

鱉甲

桃仁

茴香

丹參

徐長卿 (一 枝香)   《廣州部隊常用中草藥手冊》

 

"乙肝大三陽"

濟南中山肝病醫院權威肝病專家介紹說,乙肝大三陽是指在乙肝五項檢查中,
乙肝表面抗原(HBsAg)、
乙肝e抗原(HBeAg)、
乙肝核心抗體(抗 -HBc或HBcAb)
三項指標同時陽性。乙肝大三陽說明患者體內病毒數量較多,病毒復制活躍,

傳染性較強。如果被檢查者的血液檢查為乙肝大三陽,但 沒有臨床症狀,

肝功能也正常, 那麼他就不能被稱為乙肝病人,而只能說是乙肝病毒攜帶者
 

乙肝五項檢查分別是:

  1. 表面抗原(HBsAg)

  2. 表面抗體(抗HBs)

  3. е抗原(HBeAg)

  4. е抗 體(抗HBe)

  5. 核心抗體(抗HBc),

乙肝五項又叫乙肝兩對半。

 

乙肝小三陽

 

所謂乙肝小三陽是指在乙肝的五 項檢查 (兩對半) 檢查的五項指標中,

乙肝表面抗原(HBsAg)、

乙肝E抗體(HBeAb)

乙肝核心抗體(HBcAb)

檢測均是陽性。

豬苓加丹參,豬苓,丹參 對HBV影響:

http://www.cjim.cn/zxyjhcn/zxyjhcn/ch/reader/view_abstract.aspx?file_no=19930913&flag=1

http://www.stmopen.com/a/yiyaoweisheng/jichuyixue/zhongguozhongxiyijiehezazhi/1309373.html

服用十 全大補湯可防止肝癌發生。 [3]
 

[1] J Viral Hepat. 2013;20(7):445-452.

[2] Zhong Hua Ben Cao 中華本草

[3] Evidence Reports of Kampo Treatment 2010; Task Force for Evidence Reports / Clinical Practice Guideline Special Committee for EBM, the Japan Society for Oriental Medicine

 

 

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Last update: June 21, 2015, 4: p.m. LAH