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Herbs that are Not Compatible with Certain Drugs

 by: Joe Hing Kwok Chu

Names of Drugs

Names of Herbs

Reasons:

ampicillin ( Omnipen, Polycillin, Principen)

jia zhu tao夾竹桃
wan nian qing萬年青
fu shou cao福壽草
ampicillin is a strong inhibitor for Psuedomonas Aureginosa. If it use with the cardiac stimulating herb of jia zhu tao, wan nian qiang or fu shou cao it can cause hypokalemia and create cardiac toxicity for the herbs.

Tetracyclines

shi gao石膏
han shui shi寒水石
niu huang jie du pian牛黃解毒 片

herbs contain calcium sulfate which may combine with tetracyclines and render it ineffective.

Iron compounds, vitamin B1

shi liu pi石榴皮
wu bei zi五倍子
da huang大 黃
di yu地 榆  
hu zhang虎 杖

the herbs contain large amount of tannin acid and may result in tannin salt

Aluminium Hydroxide , Aminophylline , Sodium Bicarbonate

 
bao he wan保和 丸
liu wei di huang wan六味地黃 丸

the drugs are alkaline and the herbs are acidic.

Aspirin

 
lu rong鹿 茸
gan cao甘 草

the herbs posses the effect steroid and aspirin can stimulate the mucus lining of the stomach

corticosteroids
ginseng人參
 possible additive effect

cyclosporine

guan ye lian qiao (St. John's wort)貫葉連翹

 

Digitalis type of drug

 
zhen zhu mu珍珠母
long gu龍 骨
shi gao石膏

the herbs contain calcium ions and can increase the toxicity of digitalis and can result in arrhythmia

Digitalis type of drug

 
gan cao甘 草
  

the herb can increase the function of the drug and may cause cardiac exhaustion

Diuretics for expelling potassium

 
gan cao 甘 草
  

the herb has mineralocorticoid effect which can retain sodium and expel potassium and may cause over expelling K and result in low overly potassium.

Erythromycin. (Erythromycinum, Erythrocin, Erythrogran, Robimycin 紅黴素)

chuan xin lian穿心蓮
  
Erythromycin can inhibit the function of chuan xin lian in promoting the ability of white cells in killing bacteria.

Sulphonamides

 
wu mei烏梅
shan zha山 楂
nu zhen zi女 貞 子
wu wei zi五味子

 

may cause increase of uric acid crystal formation

Sodim bicarbonate, Aminophylline , theophyline

wu mei烏梅
shan zha山 楂
nu zhen zi女 貞 子
wu wei zi五味子

lowering the effectiveness of the drugs

warfarin, heparin

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

chi shao

赤芍

dan shen

丹參

dang gui,

當歸

e zhu

莪朮

gan qi

乾漆

garlic (da suan)

大蒜

ginseng

人參

ginkgo (bai guo, yin guo, yin xing)

白果﹐銀杏﹐銀果

hong hua

紅花

hu zhang

虎杖

huang qin

黃芩

ji xue teng

雞血藤

jiang huang

薑黃

hong hua

紅花

liu ji nu

劉寄奴

lu lu tong

路路通

ru xiang

乳香

san leng

三 棱

shui zhi

水蛭

si gua luo

絲瓜絡

su mu

蘇木

tao ren  

桃仁

tu bie chong

土鳖虫

wa leng zi

瓦楞子

wang bu liu xing

王不留行

wu ling zhi

五靈脂

xue jie

血竭

yan hu suo

延胡索

ye ju hua

野菊花

yi mu cao

益母草

yu jin

鬱金

ze lan

澤 蘭

zang hong hua

紅花

zi ran tong

自然銅

the use of these  herbs may increase the effect of the blood thinning drugs and can cause bleeding. 

phenelzine

 ginseng 人參
 ma huang 麻 黃

induces mania if used  with phenelzine.

theophyline

guan ye lian qiao (St. John's wort)貫葉連翹

 

indinavir (Crixivan)

guan ye lian qiao (St. John's wort)貫葉連翹

St. John's Wort has been shown to significantly lower indinavir (Crixivan) levels by almost 60%. [1]

interferon

chai hu柴 胡

risk of interstitial pneumonia

atropin, pepsin, and other digestive enzymes

liu shen wan六神 丸
contains arsenic, the main ingredient of xiong huang 雄黃 which is one of the ingredients of liu shen wan. Using it with atropin can cause oxidation of xiong huang and increases the toxicity.

Using liu shen wan with digestive enzyme can lower the effeciveness of the digestive enzyme.

 

indinavir (Crixivan) is a protease-inhibiting drug usually used in combination with other drugs to suppress the replication of HIV.

 

[1] http://www.tthhivclinic.com/stjohnswort.html

 

 

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Last update: April 16, 2010;  11:50 p.m. LAH

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