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Last update: May 10, 2012; 8:11 a.m. LAH

 

rěn dōng tng 忍冬藤   ( in English and Chinese 中英文)

by: Joe Hing kwok Chu    朱興國編 譯   

Pharmaceutical name:

英文藥名﹕

Caulis Lonicerae

Botanical name:

拉丁生物學名﹕

Lonicera japonica Thunb.

Lonicera confusa (Sweet) DC.  (華南忍冬)

Lonicera hypoglauca Miq. (菰腺忍冬)

Lonicera fuluotomentosa Hsu et S.C.Chneg

Pron. in Japanese:

日語發音﹕

nindoto

Pron. in Korean:

韓語發音﹕

 

Pron. in Cantonese::

粵音﹕

jan2 dung1 tang4

Other Names:

別名﹕

 
lao weng xu (old man beard)老翁鬚
jin cha gu金釵股
da pi li大薜荔
shui yang teng水楊藤
qian jin teng (thousand pieces of gold vine)千金藤
yuan yang cao (affectionate couple grass)鴛鴦草
yuan yang teng (affectionate couple vine)鷺鷥藤
ren dong cao (winter tolerating grass)忍冬草
zuo chan teng (left twisting vine)左纏藤
ren han cao (cold tolerating grass)忍寒草
tong ling cao (spirit connecting grass)通靈草
mi tong teng (honey pail vine)蜜桶藤
jin yin hua teng (gold and silver flower vine)金銀花藤
jin yin teng (gold and silver vine)金銀藤
jin yin hua gan (gold and silver flower stem)金銀花桿
tian teng (sweet vine)甜藤
you zhuan teng (right small script vine)右篆藤
you xuan teng (right turning vine)右旋藤

Common Name:

英文名﹕

 

Distribution:

產地﹕

Distributed in Liaoning, Hebei, Henan, Shandong, Anhui, Jiangsu, Zhejiang, Fujian, Guangdong, Guangxi, Jiangxi, Hunan, Hubei, Sichuan, Guizhou, Yunnan, Shaanxi, Gansu and other places.

It is mainly produced in Zhejiang, Sichuan, Jiangsu, Henan, Shaanxi, Shandong, Guangxi, Hunan and other places. It is also produced in Anhui, Gansu, Hubei, Jiangxi, Fujian, Shanxi, Yunnan, Liaoning, Hebei.

分佈於遼寧、河北、河南、山東、安徽、江蘇、浙江、福建、廣東、廣西、江西、湖南、湖北、四川、貴州、雲南、陝西、甘肅等地。

主產浙江、四川、江蘇、河南、陝西、山東、廣西、湖南等地。此外安徽、甘肅、湖北、江西、福建、山西、雲南、遼寧、河北等地亦產。

Properties

characteristics﹕

性味﹕

sweet, cold.

甘,寒。

Channels meridians entered:

 

歸經﹕

heart, lung.

心,肺。

Medical functions:

藥理﹕

 

Antibiotic effect:

The luteolin of this herb in 1:350,000 concentration can inhibit the growth of Staphylococcus aureus and Bacillus subtilis. Catarrhal bacteria also inhibited Candida albicans, typhoid, dysentery, and Proteus.

The  50% decoction of the above ground part, using the tablet trenching method, can inhibit Salmonella typhi, Shigella flexneri, Staphylococcus aureus and Pseudomonas aeruginosa. T

he 50% juice of the stems and leaves can inhibit  Salmonella typhi, Shigella flexneri and Staphylococcus aureus., but weaker than the  above ground dry parts.

It also possesses strong anti-infection effects in vivo, a strong inhibition effect on Helicobacter  suis.

Anti-inflammatory effect: Dosage of 20mg/kg for 7 days, significantly inhibited  inflammatory process in rats caused by implanted ball of wool .

Cardiovascular role:

luteolin at 5 10 concentration, can reduce the magnitude of diastolic function of the isolated frog heart, a slight decrease of the systolic amplitude, heart rate slows down, cardiac output is reduced.

Concentration of 2 10, can increase the systolic and diastolic amplitude of the isolated guinea pig heart, fast heart rate, while no direct impact on the coronary artery and blood volume.

Cardiopulmonary devices for dogs: 5-10mg of luteolin can increase the  arterial pressure but reduces venous pressure.

10mg enable lower limb blood flow in rats (33%), 5-15mg can make cats, dogs, blood pressure increased 12 -30%.

The above effects can not be  blocked by alpha-adrenergic blockers.

 0.5g/kg subcutaneous injection in rats enhanced the role of the capillary.

It lowered blood cholesterol in rabbits with experimental artery atherosclerosis.

Anti-spasm: Effects of luteolin:

Reducing spasm effect on the isolated small intestine of the rabbit and  guinea pig tracheal smooth muscle and ileum

Expectorant Effect:

Anti-cancer effects: mouse phenol red method and the test of rat capillary method, luteolin is known as a good anti-cancer effect. Luteolin inhibits the growth of NK / Ly ascites tumor cells in vitro culture.

抗菌作用:本品所含的木犀草素在1:350,000濃度時可抑制葡萄球菌和枯草杆菌的生長。對卡他、白色念珠、傷寒、痢疾、變形等菌亦有抑制作用。

忍冬地上部分50%煎劑,用平板挖溝法,對傷寒杆菌、福氏痢疾杆菌、金黃色葡萄球菌及綠膿杆菌具抑制作用;

莖葉50%鮮汁對傷寒杆菌、福氏痢疾杆菌及金黃色葡萄球菌具抑制作用,但弱於干的整個地上部分。

在體內亦有較強的抗感染作用。對 H. Suis病毒有很強的抑制作用。

消炎作用:在劑量20mg/kg7d,能明顯抑制大鼠植入羊毛球所致的發炎過程。

對心血管的作用:木犀草素在510濃度時,能降低離體蛙心的舒張期幅度,對收縮期幅度有輕度降低,心率變慢,輸出量減少。

在210濃度時,能增加離體豚鼠心臟的收縮期及舒張期幅度,心率變快,而對冠狀動脈及血容量則無直接影響。

對狗的心肺裝置,5-10mg木犀草素可使動脈壓有所增加而降低靜脈壓.

10mg可使大鼠下肢血流減少(33%),

5-15mg可使貓、犬血壓升高12-30%。

上述作用不能被α-腎上腺素能阻滯劑所阻斷。

大鼠0.5g/kg皮下注射有增強毛細血管的作用。

對兔實驗性動脈粥樣硬化有降低血膽甾醇的作用。

解痙作用:木犀草素對兔離體小腸、豚鼠氣管平滑肌及回腸有解痙作用。
 

祛痰作用

抗癌作用:用小鼠酚紅法和大鼠毛細管法試驗,木犀草素有較好的抗癌作用。木犀草素對 NK/Ly 腹水癌細胞體外培養有抑制生長的作用。

Actions & Indications:

主治﹕

Function similar to the flower jin yin hua. Primarily for treatment of abscesses and sores.

其功效如金銀花。主要作治療膿腫與潰瘍。

Chemical ingredients:[1]

化學成份﹕[1]

 
The vines contains:藤含:

chlorogenic acid

綠原酸

isochlorogenic acid

異綠原酸

loganin

地上部分含

secologanin dimethylacetal

馬錢子甙

secologanin dimethylacetal

斷馬錢子甙二甲基縮醛

vogeloside

斷馬錢子甙半縮醛內酯

epi-vogeloside[2]

表斷馬錢子甙半縮醛內酯([2]

hederagenin-3-O-α-L-rbinopyranoside

常春藤皂甙元-3-O-α-L-吡喃阿拉伯糖甙

hederagenin-3-O-β-D-glucopyranosyl(1→2)-α-L-arabinopyranoside

常春藤皂甙元-3-O-β-D-吡喃葡萄糖基(1→2)-α-L-吡喃阿拉伯糖甙

hederagenin-3-O-α-L-arabinopyranosyl-28-O-β-D-glucopyranosyl(1→6)- β-D-glucopyranoside

常春藤皂甙元-3-O-α-L-吡喃阿拉伯糖基-28-O-β-D-吡喃葡萄糖基(1→6)-β-D-吡喃葡萄糖甙

hederagenin-3-O-β-D-glucpyranosyl(1→2)-α-L-arabinopyranosyl-28-O-β-D-glucopyranosyl(1→6)-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside

常春藤皂甙元-3-O-β-D-吡喃葡萄糖基(1→6)-β-D-吡喃葡萄糖甙

hederagenin-3-O-α-L-rhamnopyranosyl(1→2)-α-L-arabinopyranosyl-28-O-β-D-glucopyranoside

常春藤皂甙元-3-O-α-L-吡喃鼠李糖基(1→2)-α-L-吡喃阿拉伯糖基-28-O-β-D-吡喃葡萄糖甙

hederagenin-3-O-α-L-rhamnopyranosyl(1→2)-α-L-arabinopyran-nosyl-28-O-β-D-glucopyrananosyl(1→6)-β-D-glucopyranoside

常春藤皂甙元-3-O-α-L-吡喃鼠李糖基(1→2)-α-L-吡喃阿拉伯糖基-28-O-β-D-吡喃葡萄糖基(1→6)-β-D-吡喃葡萄糖甙

hederagenin-3-O-α-L-rhamnopyranosyl(1→2)-α-L-arabinopyranosy(1→6)-β-D-glucopyranoside

常春藤皂甙元-3-O-β-D-吡喃鼠李糖基(1→2)-α-L-吡喃阿拉伯糖基(1→6)-β-D-吡喃葡萄糖甙glucopyranosyl(1→6)-β-D-glucopyranoside]

hederagenin-3-O-α-L-rhamnopyranosyl(1→2)-α-L-arabinopyran-nosyl-28-O-6-acetyl-β-D-glucopranosyl(1→6)-β-O-glucpyranoside

常春藤皂甙元-3-O-α-L-吡喃鼠李糖基(1→2)-α-L-吡喃阿拉伯糖基-28-O-3-乙酰基-β-D-吡喃葡萄糖基(1→6)-β-D-吡喃葡萄糖甙

oleanolic acid-3-O-β-D-glucopyansoyl(1→2)-α-L-arabinopyran-nosyl-28-O-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside

齊墩果酸-3-O-β-D-吡喃葡萄糖基(1→2)-α-L-吡喃阿拉伯糖基-28-O-β-D-吡喃葡萄糖基(1→6)-β-D-吡喃葡萄糖甙

oleanolic acid-3-O-α-L-rhamnopyranosyl()1→2]-α-L-arabinopyranosyl-28-O-β-D-glu-copyranosyl(1→6)-β-D-glucopyranoside][3]

齊墩果酸-3-O-α-L-吡喃鼠李糖基(1→2)-α-L-吡喃阿拉伯糖基-28-O-β-D-吡喃葡萄糖基(1→6)-β-D-吡喃葡萄糖甙[3]

hederagenin-3-O-α-L-rhamnopyranosyl(1→2)-α-L-arabinopyranosyl-28-O-3-acetyl-β-D-xylopyranosyl(1→6)-β-D-glucopyranoside

常春藤皂甙元-3-O-α-L-吡喃鼠李糖基(1→2)-α-L-吡喃阿拉伯糖基-28-O-3-乙酰基-β-D-吡喃木糖基-α-L-吡喃阿拉伯糖基(1-α-L-吡喃阿拉伯糖基6)-β-D-吡喃葡萄糖甙[hederagenin-3-O-α-L-rhamnopyranosyl(1-α-L-吡喃阿拉伯糖基(1→6)-β-D-吡喃葡萄糖甙

hederagenin-3-O-α-L-rhamnopyranosyl(1→6)-β-D-glucopyranoside][4]

常春藤皂甙元-3-O-α-L-吡喃鼠李糖基(1→2)-α-L-吡喃阿拉伯糖基-28-O-β-D-吡喃木糖基(1→6)-β-D-吡喃葡萄糖糖甙[gederangenin-3-O-β-D-吡喃木糖基(1→6)-β-D-吡喃葡萄糖甙[4]

Also contain: iron, barium, manganese, zinc, titanium, strontium, copper and other trace elements [5].

還含:鐵、鋇、錳、鋅、鈦、鍶、銅等微量元素[5]。

young stems contain: secoxyloganin[6]

幼枝含斷氧化馬錢子甙[6]

Leaves contain:葉含:

luteolin

木犀草素

loniceraflavone

忍冬素

3-methoxy-5,7,4-trihydroxyflavaone

3-甲氧基-5,7,4-三羥基黃酮

luteolin-7-hamnoglucoside,loni-cerin

木犀草素-7-鼠李葡萄糖甙即忍冬甙

luteolin-7-O-digalactoside

木犀草素-7-O-雙半乳糖甙

loniceraflavone-6-rhamnohlucoside

忍冬素-6-鼠李葡萄糖甙

caffeic acid[7]

異綠原酸及咖啡酸[7]

vanillic acid [8]

香草酸喜[8]

venoterpine [8]

樹次鹼

The above ground portion of Lonicera hypoglauca Miq. contains:菰腺忍冬地上部分含:

4-hydroxy-2,6-di-(4-hy-droxy-3-methoxy)phenyl-3,7-dioxobicyclo[3,3,0]octane

左旋-4-羥基-2,6-二-(4-羥基-3-甲氧基)苯基-3,7-二氧雙環[3,3,0]辛烷

n-10-nonaconsanol

正-10-二十九醇

scopoletin

東莨菪素

syringic acid

丁香酸

β-sitosterol

β-谷甾醇

β-sitosterol glucoside [9].

β-谷甾醇葡萄糖甙 [9].

Daly Dosage:

每日用量﹕

Take orally: for decoction use 10 to 30 g; or into pills, or in powder form or add or make into pills, or soak in rice wine.

External application: use appropriate amount, or boil with water and wash affected areas or grind into powder and apply. Fresh herb can also be pounded and apply to affected areas.

內服:煎湯,10-30 g;或入丸、散;或浸酒。外用:適量,煎水熏洗,或熬膏貼,或研末調敷衍,赤可用鮮品搗敷。

Samples of formulae:

處方舉例﹕

oesteomyelitis  骨疽

Modern Research:

現代研究﹕

 

Toxicity & Cautions:

毒素與禁忌﹕

Not to use in case of pixu (spleen deficient) 

脾虛,泄瀉不止者禁用。

[1]  Zong Hua Ben Cao 中華本草

For bibliography, see Zong Hua Ben Cao

 

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