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White blood Cell (leukocyte) count WBC
by: Joe Hing kwok Chu
Reference Range
Adult Reference Range
4.5~11.0 X 103/µL (SI units: 4.5~11 X109/L
Pediatric Reference Range
New born: 900 ~ 30,000/µL
2 weeks old: 500 ~ 20,000/µL
1 year old: 6000 ~ 18,000/µL
4 years old: 5500 ~ 17,000/µL
10 years old: 4500 ~ 13,5000/µL
WBC Differential
Determines the percentage of each type of white blood cell in a sample. To get the actual number of each type of white blood cell in the sample, multiply the percentage of the different white cells by the total count of white blood cells.
Adult Reference Range
Pediatric Reference Range
Newborns: same as adult .
4 weeks: Neutrophils drop to 40%;
Lymphocytes rise to 45% .
10 months -20 years: a gradual return to adult ratio. Purposes of the Test 1. Diagnosing diseases 2. Evaluating the stages of a particular disease as in monitoring the the patient's progress and the effects of chemotherapy.
Interfering Factors
Drugs that decrease the eosinophil count:
corticosteroids. Drugs that decrease the
Lymphocyte count:
corticosteroids, and
chemotherapeutic agents. Drugs that increase the
neutrophils count: epinephrine, digitalis,
heparin, and
corticosteroids. Time of the blood sample drawn: low in the morning and high in the afternoon.
Terms:
- Band: Immature neutrophil.
- Basophil: White blood cell that increases in response to parasitic infections and allergic reactions.
- Differential: Blood test that determines the percentage of each type of white blood cell in a person's blood.
- Eosinophil: White blood cell that increases in response to parasitic infections and allergic reactions.
- Leukocytosis: A white count increased to over 10,000/L.
- Leukopenia: A white count decreased to less than 4,000/L.
- Lymphocyte: White blood cell that fights viral and some bacterial infections by direct attack or the production of antibodies.
- Monocyte: It removes debris and microorganisms by
phagocytosis.
- An increased number of monocytes in the blood (monocytosis) occurs during a variety of conditions including severe infections, chronic infections, auto-immune disorders, blood disorders, and cancers. A low number of monocytes in the blood (monocytopenia) can occur in response to the releasing of toxins into the blood by certain types of bacteria, receiving chemotherapy or corticosteroids.
- Neutrophil: White blood cell that increases in response to bacterial infection. It removes and kills bacteria through phagocytosis. A low number of neutrophil increases the risk of infection.
- Segmented neutrophils (polymorphonuclear leukocytes, or segs) are the mature phagocytes that migrate through tissues to destroy microbes and respond to inflammatory stimuli.
- Phagocytosis: A process by which a white blood cell envelopes and digests debris and microorganisms to remove them from the blood.
Also see:
SARS and White Cell Count Study
Back to Complete Blood Cell Count
How white cell cannabalize virus infected cells.
Last update: Feb 18, 2009;
0:59 a.m. LAH
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