| Pharmaceutical
name: 英文藥名:
|
Fructus Evodiae Rutaecarpae |
| Latin
botanical name:
拉丁學名:
|
Evodia rutaecarpa
(Juss.) Benth., Evodia rutaecarpa
(Juss.) Benth. var. officinalis (Dode)
Huang,
|
| Pron. in Japanese:
日語發音:
|
goshuyu |
| Pron. in Korean:
韓語發音:
|
osuyu |
| Pron. in Cantonese:
粤語發音:
|
ngu chu yu |
| Common Name:
英文名:
|
evodia fruit |
|
Other
Names:
別名: |
wu yu 吳萸,qu yao zi
曲藥子,fu la zi
伏辣子,cha la 茶辣,chou
pao zi 臭泡子。 |
| Distribution:
分佈: |
Guizhou, Sichuan, Guangxi,
Hunan, Yunnan, Shaanxi, Zhejiang
贵州, 四川,廣西,湖南,云南, 陝西, 浙江。 |
| Properties (characteristics):
性味:
|
acrid, bitter, hot, mildly
toxic.
辛,苦,熱,有小毒。
|
| Channels
(meridians) entered:
歸經:
|
kidney, liver, spleen,
stomach 腎,肝,脾,胃。
|
| Actions
& Indications:
主治:
|
warms the middle, lower
qi, rids of cold of stomach, lower blood pressure, for vomiting, excess
acid of stomach, pain in solar plexus, cold type of hernia, cold and
dampness of swelling of legs. Lead fire downward.
溫 中 下 氣 , 止 痛 除 濕 , 善 於 溫 散 肝 胃 之 寒 , 降
血 壓。
嘔 吐 吞 酸 , 胃 脘 痛 , 腹 內 絞 痛 , 泄 瀉 , 寒 疝 痛 , 寒 濕
腳 氣 。
|
| Medical Function:
药理:
|
Relaxes blood vessels
by promoting the excitement of the inner skin of blood vessels, clearing
the pathway of calcium ion, and releasing nitrogen oxide.
- 促進血管內皮興奮,打通鈣離子的通道,釋放出一氧化氮,以致放鬆血管。
- 抑制血小板聚集。抑制血小板血栓及纖維蛋白血栓形成。
- 鎮痛,升高體溫作用,大量時能興奮中樞,並引起視力障礙﹐錯覺。
|
| Chemical
ingredients:
化學成份:
|
1.limonin 檸檬內酯 [1];rutaevine 吳茱萸苦素[2];
evodol吳茱萸內酯醇[3]; obacunone 黃柏酮[4]; rutaevine acetate 吳茱萸苦素乙酯[5]; 12
alpha-hydroxylimonin 12 a-羥基檸檬內酯; 12 alpha-hydroxyevodol 12
a-羥基吳茱萸內酯醇[6]; 6alpha-acetoxy-5-epilimonin;
6alpha-acetoxy-5-epilimonin[6,7]; Jangomolide[8]; GraucinA[9]. 2. (1).evocarpine
吳茱萸卡品鹼[10];
dihydroevocarpine; 1-methyl-2-undecyl-4 (1H)-quinolone; 1-methyl-2-pentadecenyl-4(1H)-quinolone[11];
1-methyl-2-[(Z) -6 -undecenyl]-4 (1H)-quinolone; 1-methyl-2-[Z) -6-pentadecenyl]-4
(1H) -quinolone;1-methyl-2-[(Z)-10-pentadeceny;]-4 (1H)-quinolone; 1-methyl-2-(6Z,
9Z)-6, 9-pentadecadienyl) -4 (1H) -quinolone; 1-methyl-2-([4Z, 7Z])
-4, 7-tridecxadienyl) -4 (1H)-quinolone[6].
(2). evodiamine; rutaecarpine; wuchuyine; hydroxyevodiamine
羥基吳茱萸鹼; dihydrorutaecarpine;
14-formyldihydrorutaecarpine[12];Goshuyuamide-I,
Goshuyuamide-II[13]; evodiamide[14].
(3).N, N-diumethyl-5-methoxy tryptamine; N-methylanthranylamide;
disynephrine[15]; cGMP[16].
3. arachidoside; isopentenyl-flavone[17].
4. evoden; alpha-ocimene; cis-beta-ocimene.
5. evodinone; evogin[18].
|
| Dosage:
用量:
|
3 to 9 g. Use with
gan cao to reduce side effects.
3∼9克。加甘草可以减輕其副作用。
|
| Samples of formulae: |
For headaches caused by
vasomoter dysfunction:
Name of formula:
wu zhu yu
tang
Composition: wu zhu yu, ren shen,
da zao, shen jiang.
吳茱萸湯﹕由吳茱萸﹐人參﹐大棗﹐生姜四味所組成,所治的厥陰頭痛,即血管神經性
頭痛。
|
| Modern
Research: 现
代研究:
|
"Antidementic Drug Discovery
from Oriental Herb Medicine: Dehydroevodiamine.HCl (DHED) extracted
from Evodia Rutaecarpa Bentham prevents Impairment of Learning and Memory
and Neuronal loss" - Cheol Hyoung Park (Korea).
Feeding the decoction to dogs, showed that it lowered
the blood pressure but when combined with gan cao, the effect disappeared.
The lowering of blood pressure is the result of the expansion of the
peripheral blood vessels and it is caused by secretion of histamine.
The decoction showed that it affect the activities of the small intestine
of rabbits. Higher concentration of decoction inhibited the activities
and lower concentration of it enhanced the activities.
用其煎劑給狗灌胃,有明顯的降壓作用,但與甘草配伍,其降壓作用消失。其壓降作用主要是擴張外周血管所致,且與組織胺釋放有關。其煎劑對家兔小腸活動的影響。低濃度時興奮,高濃度時抑制。
|
| Cautions:
禁忌:
|
not suitable for
shi zheng (strong pattern) ,
yinxu (yin deficient) and high fire
body type. 不適用於實證,
陰虛火旺之體質。
|