ge gen  (kudzu)

 

translated and edited by: Joe Hing kwok Chu

Present Day Applications:

現代應用﹕

being used in heart and brain diseases due to lack of blood circulation.

用于缺血性心腦血管疾病的治 療 。

Pharmaceutical name:

英文藥 名﹕

Radix Puerariae

Flos Puerariae

Botanical name:

學名﹕

Pueraria lobata (Willd.) Ohwi;

Pueraria  thunbergiana (S. etZ.) Benth.;

Pueraria  hirsuta (Thunb.) Schneid.;

Pueraria  pseudohirsuta Tang et wang

Pueraria thomsonii Benth.

Pron. in Japanese:

日語發音﹕

kakkon

Pron. in Korean:

韓語發音﹕

kalgun

Pron. in Cantonese

粵音﹕

got3 gan1

Other Names:

別名﹕

gan gen 乾 根﹐ gan ge gen 乾葛根

Common Name:

英文名﹕

kudzu root, pueraria

Distribution:

產地﹕

Hunan, Henan, Guangdong, Zhejiang, Southeast Asia, North America.

湖南,河南,廣東,浙 江,東南亞,北美洲等地。

Properties

(characteristics)﹕

性味﹕

acrid, sweet, neutral

辛,甘,性平。

Channels (meridians) entered:

 

歸經 ﹕

spleen, stomach

脾﹐胃。

Medical functions:

藥理﹕

 

Medical Functions:

  • effect on smooth muscle: it contains ingredients that can contract and relax the smooth muscles

  • effect on coronary blood vessels: relaxes the blood vessels

  • anti-arrhythmia

  • enhances the function of the heart

  • lowers blood pressure and lowers the resistance of peripheral  blood vessels

  • beta energetic blocking effect

  • inhibits platelet coagulation

  • lower blood sugar

  • inhibits growth of cancer cells and induces differentiation of cancer cells. (Normally cancer cells do not differentiate, so it never loses its potential for growth. )

  • anti-oxidation

  • improves memory

  • improves eyesight

    The following will be translated. If you need them in a hurry, consult our Research Librarian

    http://www.ceps.com.tw/ec/ecjnlarticleView.aspx?atliid=376225&issueiid=28832&jnliid=2479

     

Actions & Indications:

主 治﹕

Diaphoretic (producing or increasing perspiration), antispasmodic, muscle relaxant, antipyretic, help to ripen measles, stopping diarrhea.

Being used in fever and headache in cold or flu, spastic muscles, thirst, diabetes, diarrhea, acute ileus (intestine blockage), measles ripening difficulty, in alcohol hangover, alcohol withdrawal, angina, hypertension, smoking, alcohol, early stage of acute deafness.

Shoots are used as a lactagogue.

The starch is being used in treating diarrhea. Do not add sugar to the starch. See a commercial package of starch here.

 

Chemical ingredients:

化 學成份﹕

Flavonoids

黃酮類

7-xyloside puerarin

7-木糖葛根素

3'-hydroxypuerarin

3'-羟基葛根素

formononetin

芒柄花素

genistein

金雀异黄素

methylpuerarin

甲基葛 根素

daidzein

大豆素

daidzin

大豆甙

puerarin

葛根素

puerarin-7-xyloside

葛根素-7-木 糖甙

4’-6’-O-diacetylpuerarin

4ˊ,6〃-O-二 乙葛根素

7,4′-diglucoside

7,4′- 二葡萄糖甙

xylopueratin

木葛 根素

miroestrol

 

Glicoside:

配糖體:

4-O-D-glucoside

4-O-D-配 糖

8-C-apiosyl-glucosides

8-C-芹 菜糖基-配 糖

pueroside A, B

葛甙 A, B

Pueranol

 

Triterpenoids:

三萜類:

sophoradiol,

槐二醇

soyasapogenols A, B,

大豆皂甙

cantoniensistriol

 

Alkaloid :

生物鹼 ﹕

 kassein

卡賽因

Saccharides:

糖類﹕

starch (10-15%)

澱粉 (10-15%)

D-mannitol

D-甘露糖醇

D-(±)pinitol

D-(±)松 醇

Saponins:

皂素:

β-sitosterol

β-谷 甾 醇

kudzusapogenol A, B, C

葛根皂草精醇

6,7-dimethoxycoumarins

6,7-二甲氧基香豆精

5-methylhydrantoin

5-甲基海因

Arachidic acid

花生酸

Dosage:

用量﹕

3 to 12 g (dried herb). Fresh herb can be used a few times more.

Samples of formulae

:處方舉例﹕

Name of Formula: ge gen tang

方名﹕葛 根湯

Modern Research:

現 代研究﹕

Ge gen was first described in the Chinese materia medica, Shen Nong Ben Cao  ( 200 B.C.) .  Both the roots and flowers of ge gen have been used to treat alcohol abuse, drunkenness, and hangover ( "jiu du" or alcohol poisoning) safely and effectively in China for more than a millennium. [1]

Now it has been tested in addiction to smoking and is considered to have the same effect, reducing the addiction in a month time.

Puerarin promotes osteoblast to differentiate by influencing the activity of ALP and promotes bone formation by the meditation of estrogen receptor. [1]

Toxicity & Cautions:

 

Allergy reaction of injectiones of puerarin: there are cases of hemolytic reaction and resulted in death.

Not to use in cases of instant sweating during summer.

Using too much can damage the digestive function.

Steve: do not worry about the  injectiones  which is to inject the extract to the blood vessels. We are talking about making soup for eating.

 

For more information, click here.

毒素與禁忌﹕

葛根素注射液目前在臨床 上 廣 泛用於缺血性 心腦血管疾病的治 療 。因其臨床 應 用療 程長,易發 生 藥 物蓄 積 ,產生毒性。隨著葛根素注射液在臨床 應 用的不斷擴展,有關 不良反應 報 告也 有所增加。

  本品所致的可疑不良反應 主要表現為 各種類 型的過敏反應 ,以藥 物熱,皮疹,過敏性哮喘,全身性過敏反應 包括過敏性休克等表現為 主。發生過敏反應 的潛伏期從 十幾分鐘 到13天不等,多數在連續用藥 過程中出現,經 停藥 及抗過敏治 療後 恢 復。葛根素注射液還可引起溶血性貧血,患者出現腰痛,排尿 困難 和血尿,一般停藥 和經 對 症藥 物治 療後緩解,但有因溶血性貧血致死病例。此外本品還可引起肝,腎損害,患者出現四肢乏力,食欲不振,黃疸以及轉氨 酶和血鉀,尿素氮等明顯升高,經 過對症治 療後 肝,腎功能恢 復 正常。

 

註﹕

卡賽因 Kassein 對平滑肌有收縮作用。對胃 排空延遲者俱有促進作用。

[1} Proceedings of the National Academy of Sciences 2000;97:12493-12497.

A manuscript