Topically, pau d'arco appears to have varying amounts of antibacterial, antifungal, antiprotozoal, and antiviral properties. It may be anti-inflammatory, as well; but none of these potential topical uses has been well-studied. In Central American and South American countries, pau d'arco is used topically to treat minor skin injuries, such as insect bites, as well as more serious conditions such as psoriasis. It has also been used as a mouthwash and to treat vaginal yeast infections.