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lei gong teng, Tripterygium wilfordii Hook. f.

Translated and edited by: Joe Hing Kwok Chu

　Description

The herb of lei gong teng comes from the roots, leave and flowers of the tripterygium wildordii Hook. f. It is collected during summer and autumn. Lei gong teng is a deciduous scandent vine growing to 12 meters, with brown, angular, downy twigs. The leaves are light green glabrous on top and paller, glaucous and pubescent on beneath, with crenate margins and pointed apexes, ovate to elliptic, 5-15 cm long, 2.5 - 7 cm wide. The scented hermaphrodite (having male and female organs) flowers, which bloom in September, are small and whitish with five petls and are about 9 mm across, in terminal panicles in July. Fruits are 3-winged, and brownish red about 1.5 cm long.

The plant can grow in light (sandy), medium (loamy) and heavy (clay) soils. It can survive in acid, neutral and basic (alkaline) soil. It can grow in semi-shade (light woodland) or no shade. It requires moist soil.

Pharmaceutical name:	Radix Tripterygium wilfordii
Latin botanical name:	Tripterygium wilfordii Hook. f.
Pron. in Cantonese:	lui kong teng
Common Name:	three-wing-nut
Distribution:	mainland China, Taiwan, Burma
Properties (characteristics)	bitter and very toxic
Actions & Indications:	for: anti-inflamation, kills worms, resolves toxin, treating proteinuric real disease, using as immunosupressive agent on autoimmune diseases.
Chemical ingredients:	1. Saponins: (1). wilforgine, wilforgine-B,wifordine, wilfornine, wilfortrine, wilforttrine-D, wilforzine[1-3], wilformine [4], wilfordinc acid, hyudroxywilfordie acid [5],wilfornine [6], neowilforine [7] (2). celacinnine, celafurine, celabenzine, celallocinnine [8-9] (3). triptofordinine A-1, A-2 [10], triptofordin D-1, D-2, E [11], triptofordin A, B, C-1 C-2 [12],triptofordin F-1, F-2, F-3, F-4 [13] 2. (1). triptolide, tripdiolide, triptonide,[14-15],tripterolide[16]. (2.). triptolidenol [16-17], tripnolide [18],neotriptophenolide, triptophenolide methyl ether [19], isoneotrip-tophenolide, hypolide methyl ether [20]. (3). triptonoterpene, triptonoterpene methyl ether [17], triptonoterpenol [21]12-ydroxy-abieta-8, 11, 13 -trien-3-one, 11-hydroxy-14-methoxy-abieta-8, 11-hydroxy-14-methoxy-abieta-8, 11, 13-trien-3-one [22]. 3. (1). wilforlide A, wilforlide B [23]. (2). tritotriterpenoid lactone [24], tretotriterpenic acid A [25,26],tritotriterpenic acid B [27], tritotriterpenic acid C [28], 3-epikatonic acid [29], polpunonic acid, triptodihydroxy acid methy ester [30], tripterine [31]. (3). 3,24-dioxofridelan-29-oic acid [29], salaspermic acid [29,32]. 4. wilfornide [20] 5. 1,8-dihydroxy-4-hydroxymethyl anthraquinone [33]. 6. syringareisnol [34]. 7. dulcitol, glucose [31], tanin
Medical Functions:	1. Effects on immune system 2. Effects on anti-inflamatory 3. Effects on anti-cancer 4. Effects on contraception 5. Effects on urinary system 6. Effects on anti organism and worms 7. Other Effects 8. Inside body 9. Effects of toxicity
Other Research:	Four compounds purified from T. wilfordii may confer protection against the FSGS (focalsegmental gomerulosclerosis) factor.^a
^{Research on Pharmacological Processes:}
Modern Clinical Application:
Cautions:	Long term use of lei gong teng could significantly decrease bone mineral density of levels in female systemic lupus erythematosus (SLE)^b

Other related websites:

http://www.pagansonline.com/pagansonline/euonymus.htm

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(a). M. Sharma, R. Sharma, XL Ge, R.S.Rdy, E.T.McCarthy, V. J. Savin, Medical College of Wisconsin, Milwaukee, WI, U.S.A.

(b). Department of dermatology, Huashan hospital, Shanghai Medical University, Shanghai 200040, China (Huang L and Feng SF); Radiology Institute, Shanghai Medical University, Shanghai 200040, China (Wang HF).

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