Drugs contraindication for Patients with Enlarged Prostate

Translated and edit by: Joe Hing Kwok Chu 朱興國編譯

Antipsychotic drugs:

such as Chlorpromazine,Fluphenazine,  ( droperidol alcohol ) Haloperidol , these drugs can cause difficulty in urinating .

Antidepressant drugs: 

such as imipramine, doxepin, , Amitriptyline Hyddrochloride, Chlorimipramine, these drugs also can cause urinary difficulty.

Asthma drugs: 

such as aminophylline, theophylline, ephedrine, isopropyl salbutamol, orciprenaline  can cause difficulty in urinating .

Heart disease, cerebrovascular disease drugs:

such as propranolol (Inderal), nifedipine, verapamil hydrochloride, can cause urinary suppression due to the  bladder muscle tension.

Abdominal pain with drugs:

such as Atropa Belladonna, atropine, buscopan ( scopolamine ), Butylbromide, anisodamine (654-2) Anisodamine,  Atropinum Methobromidum, Mebropinum, Dropine, anisodine, Orpheum bromide, Oxyphenonium, propantheline, Propantheline Bromide (Pro-Banthine) , can cause detrusor relaxation, resulting in urine retention.

Potent diuretics:

such as furosemide , ethacrynic acid etc. can cause electrolyte imbalance, leading to urine detention . It should be replaced by those who have an enlarged prostate with medium potency diuretics such as hydrochlorothiazide, bendroflumethiazide, or with lower potency diuretics such as spironolactone, acetazolamide etc.

Antihistamine:

 such as phenergan , Pizotifen , dimenhydrinate , chlorpheniramine , phenindamine tartrate (thephorin ), azatadine , mequitazine can increase the difficulty urinating. They can be replaced by astemizole.

Others:

Others, such as Hydroxyzine, Isoniazid, Rimifon, Mecamylamine hydrochloride, Venoruton, Trioxyethylrutin) and traditional Chinese medicine jie shi, etc., can also lead to urinary retention.

External application drugs:

such as atropine and ephedrine nasal drops , etc., can not be ignored .

It needs to be pointed out that , prostatic hypertrophy should prevent colds or flu and alcohol consumption. It is because the commonly used anti-cold medicine , many contain chlorpheniramine . Using it, it can exacerbate the disease and drinking alcohol can make prostate congestion, edema, and even worse.

Back to prostate enlargement and urination difficulty.
 

前列腺肥大病人應忌用之藥物

前列腺肥大病人應忌用：
 

抗精神病藥 如氯丙嗪（冬眠靈）Chlorpromazine，氟奮乃靜（Fluphenazine），氟哌啶醇（氟哌醇）Haloperidol 等，這些藥可引起排尿困難。
 

抗抑郁藥 如丙咪嗪（米帕明）Imipramine ，多慮平（多塞平）Doxepin（Sineguan，Adapin，Quitaxon）, 阿米替林 Amitriptyline Hyddrochloride，氯米帕明 Chlorimipramine（Anafranil）等，這些藥也會誘發尿閉症。
 

平喘藥 如氨茶鹼 Aminophylline，茶鹼 theophylline，麻黃素 ephedrine 及異丙喘寧（奧西那林）orciprenaline 等，均可導致排尿困難。
 

心，腦血管病用藥 如心得安（普萘洛爾）Propranolol (Inderal)，心痛定（硝苯地平）Nifedipine 及異博定（維拉帕米）Verapamil Hydrochloride，皆會因抑制膀胱肌而發生尿瀦留。
 

胃腸止痛有藥 如顛茄Atropa Belladonna，阿托品 atropin，解痙靈（東莨菪鹼）Scopolamine Butylbromide，山莨菪鹼（654-2）Anisodamine，胃瘍平Atropinum Methobromidum, Mebropinum, Dropine，樟柳鹼 Anisodine及安胃靈（奧芬溴銨）Oxyphenonium，普魯本辛（丙胺太林）Propantheline Bromide (Pro-Banthine)等，均會使膀胱逼尿肌鬆弛，造成尿閉症。
 

強效利尿藥 如速尿（别名: 利尿靈, 呋喃苯胺酸 , 呋塞米;腹安酸;利尿磺胺;利尿靈;速尿;速尿靈)Furosemide ,Frusemide, LASIX, Diural, Furanlral, Seguril, Urex，利尿酸（依他尼酸）Etacrynic Acid 等，可引起電解質失去平衡，進而導致尿瀦留。故有前列腺肥大者應改用中效利尿藥，如雙氫克尿噻【別名】 雙氫克尿噻;雙氫氯噻嗪;雙氫氯散疾;雙氫氯消疾,氫氯噻嗪【外文名】Hydrochlorothiazide ,Esidrex, DCT, ORETIC, Hydrodiuril, Dihydrochlorothiazide，苄氟噻嗪，或用低效利尿藥，如安體舒通，乙酰唑胺等。
 

抗過敏藥: 如非那根，苯噻啶 ，乘暈寧，扑爾敏，抗敏胺，與阿扎他定，美喹他嗪等，均會增加排尿困難，可改用阿司咪唑。
 

其它如安他樂 Hydroxyzine，異煙肼 Isoniazid. (雷米封) Rimifon，美加明 (Mecamylamine hydrochloride)，維腦路通(Venoruton). 三羥乙蘆丁 (Trioxyethylrutin)及中藥桔 實 等，也可導致尿瀦留。
 

外用藥如阿托品滴眼液與麻黃素滴鼻液等，也不容忽視。
 

需要強調指出的是，前列腺肥大者應預防感冒並禁酒，因目前常用的抗感冒藥，很多含有扑爾敏(Chlorpheniramine)，服後會加劇病情；飲酒能使前列腺充血，水腫，能劇病情。

按此回到前列腺腫大而致排尿困難網頁。

A manuscript... writing, translating and proofreading  in progress

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